Senior Scientist in Oncology Targeted Discovery

AstraZeneca is seeking a Senior Scientist to join the Oncology Targeted Discovery team in Cambridge, MA. The role involves designing and conducting in vitro experiments to evaluate drug targets, identify novel targets for antibody drug conjugate payloads, and lead projects from target identification to validation. Responsibilities include assessing cancer cell function, analyzing experimental data, integrating literature and internal findings, and collaborating with cross-functional teams to advance oncology drug discovery. The position requires expertise in cancer biology, cell signaling, molecular biology, and experience with high-content imaging, CRISPR technologies, and transcriptomic data analysis. Preferred qualifications include experience in drug discovery programs, assay development, and bioinformatics skills.